Pdf proposed modifications to the duke criteria for the. Infective endocarditis is an infection of the inner surface of the heart, usually the valves. The sensitivity of the duke criteria was also good to excellent, varying from 71%. Clinical criteria are 2 major, 1 major plus 3 minor or 5 minor criteria e. Diagnosis and management of infective endocarditis. For adequate diagnostic sensitivity, transesophageal echocardiography is the preferred modality used in patients designated highrisk or those in whom transthoracic. Modified dukes criteria for diagnosis of infective endocarditis pdf 8. According to the modified duke criteria 7 patients had definite ie. Its intracardiac effects include severe valvular insufficiency, which may lead to. The duke ie database contains records collected prospectively on 800 cases of definite and possible ie since 1984. Guidelines for the management of infective endocarditis. Vegetations may result in valvular incompetence or obstruction. Ralph corey2,3 from the divisions of 1cardiology and 2infectious diseases, and departments of 3medicine and 4pediatrics, duke university. Please visit the project page for details or ask questions at wikipedia talk.
European association for cardiothoracic surgery eacts, the european association of nuclear medicine eanm. The modified duke criteria are a set of clinical criteria set forward to establish the diagnosis of infective endocarditis. Endocarditis diagnostic criteria modified duke criteria. Dukes criteria for diagnosis of infective endocarditis. Diagnostic criteria and problems in infective endocarditis. Individual value of each of the duke criteria for the. The first is a positive blood culture for endocarditis. Pathologic criteria are histological or culture confirmation ofpathologic criteria are histological or culture confirmation of vegetation or emboli. It comprises of 8 criteria divided in major and minor categories. Established in 1994 by the duke endocarditis service and revised in 2000, the duke criteria are a collection of major and minor criteria used to establish a diagnosis of infective endocarditis. Positive blood culture results for ie and evidence of endocardial involvement from echocardiography, are the two major duke criteria. Duke criteria for infective endocarditis calculator. Utilization of specific echocardiographic findings.
Dukes criteria were used on 83 patients examined by tee in a. Duke criteria for infectious endocarditis diagnosis. Duke criteria for infective endocarditis durack dt, lukes as, bright dk. It is the dedication of healthcare workers that will lead us through this crisis. Antibiotic treatment of infec tious endocarditis depends on. This page includes the following topics and synonyms. Acute infective endocarditis aie is a difficult disease to suspect and diagnose. Methods both classifications were applied in 93 consecutive patients with.
There are two major criteria for infective endocarditis. Infective endocarditis has been recognized as a clinical entity since the 1950s. Pdf proposed modifications to the duke criteria for the diagnosis. International collaborative on endocarditis 1779 cases, 39 centers 20002003 s. With use of new duke criteria, 405 episodes of suspected endocarditis were previously classified as definite, possible, or rejected endocarditis. Echocardiogram supportive of infective endocarditis. Negative predictive value of the duke criteria for. Ralph corey, md, joseph kisslo, md, and the duke endocarditis service with use of new duke criteria, 405 episodes of sus. Pdf although the sensitivity and specificity of the duke criteria for the diagnosis of infective endocarditis ie have been validated by. Modified dukes criteria for diagnosis of infective. For adequate diagnostic sensitivity, transesophageal echocardiography is the preferred modality used in patients designated highrisk or those in whom transthoracic echocardiography would likely be difficult. Nowadays, the duke criteria are the clinical gold standard diagnostic test though obviously, pathology is the true gold standard but note that the duke criteria are certainly not completely sensitive and may be nonspecific, depending on the case.
Main complications of leftsided valve ie and their management. The purpose of this survey was to elaborate clinicians knowledge and opinion on relevant heart conditions as a duke minor criterion for the diagnosis of ie. A sensitive, specific, and rapid diagnosis of infective endocarditis ie is important for. Infective endocarditis ie is frequently difficult to diagnose cepts, including.
Value and limitations of the duke criteria for the diagnosis of. Classification of infective endocarditis by dukes criteria and. Penicillins in endocarditis should always be combined with aminoglycosides because of the eagle effect. Objectives the purpose of this study was to assess the value and limitations of duke criteria for the diagnosis of infective endocarditis ie. Histologic, vegetation or intracardiac abscess present, confirmed by histology showing active endocarditis, short of definite, but not rejected, no pathologic.
Duke criteria for infective endocarditis inflammatory heart. Duke criteria for infective endocarditis inflammatory. Complications may include backward blood flow in the heart, the heart struggling to pump a sufficient amount of blood to meet the bodys needs heart failure, abnormal. Although the sensitivity and specificity of the duke criteria for the diagnosis of infective endocarditis ie have been validated by investigators from europe and the united states, several shortcomings of this schema remain. Clinical criteria for possible endocarditis requires at least one major criterion and one minor criterion, or three minor criteria. The duke criteria for infective endocarditis provides standardized diagnostic criteria for endocarditis. Using the model of jones criteria for rheumatic fever, the duke criteria for infective endocarditis combine major and minor clinical criteria. Click on the image or right click to open the source website in a new browser window. The endocarditis team chooses the type, duration, and mode of followup of antibiotic therapy. This is a health tool that helps clinicians diagnose infective endocarditis, a condition that is quite challenging to diagnose. Nov 25, 2016 the term predisposing heart condition is used as an indication of antimicrobial prophylaxis to prevent infective endocarditis ie and as a criterion for diagnosing ie according to modified duke criteria. Jul 01, 2015 using the model of jones criteria for rheumatic fever, the duke criteria for infective endocarditis combine major and minor clinical criteria. Excludes single positive cultures for coagulasenegative staphylococci and organisms that do not cause endocarditis. The clinical diagnosis of infective endocarditis ie has.
Negative predictive value of the duke criteria for infective. Proposed modifications to the duke criteria for the diagnosis of infective endocarditis. Infective endocarditis ie is an infection of the endocardial surface of the heart, which may include one or more heart valves, the mural endocardium, or a septal defect. The modified duke criteria can be used to help diagnose ie box 2. Duke criteria for the diagnosis of endocarditis definite.
Endocarditis, bacterial subject areas on research a comparison of hivpositive patients with and without infective endocarditis. Many studies have now demonstrated the superiority of the duke. Pts with abnormal valve due to rheumatic valvular disease, prosthetic valve, mitral valve prolapse with regurgitation, chd, aortic stenosisregurgitation. The duke criteria are a set of clinical criteria set forward for the diagnosis of infective endocarditis. Tee recommended as first test in the following patients.
It may cause fever, heart murmurs, petechiae, anemia, embolic phenomena, and endocardial vegetations. The duke criteria gave diagnostic weight to bacteremia with staphylococci or enterococci only, on the basis of the location of acquisition and with. According to the duke criteria, diagnosis of infective endocarditis can be definite, possible, or rejected. Baddour et al infective endocarditis in adults 1437 a diagnosis of ie with the original duke criteria was based on the presence of either major or minor clinical criteria tables 2 and 3. Clinical criteria for definite endocarditis requires two major criteria, or one major and three minor criteria, or five minor criteria. Nov 26, 2016 there are two major criteria for infective endocarditis. To assess the value of each duke criteria for the diagnosis of infective endocarditis ie. The duke criteria for the diagnosis of endocarditis provide a systematic approach for diagnosing both native valve endocarditis nve and pve.
Evaluation of new clinical criteria for the diagnosis of infective. This article is within the scope of wikiproject medicine, which recommends that medicinerelated articles follow the manual of style for medicinerelated articles and that biomedical information in any article use highquality medical sources. This should forward to infective endocarditis, not this page. In 1955, the american heart association aha first established guidelines for the treatment of infective endocarditis. Clarifications of the duke criteria for infective endocarditis abstract 128. Endocarditis will cause bacteremia and septic emboli. Positive blood culture for typical infective endocarditis organisms. This is a pdf document titled modified dukes criteria for diagnosis of infective endocarditis.
In our series, the sensitivity of echocardiography combining tte and tee was 93%, similar to. Jun 30, 2018 acute infective endocarditis aie is a difficult disease to suspect and diagnose. Fulfilling the criteria, and a subsequently definitive diagnosis includes either having two major criteria, one major and three minor criteria, or five minor criteria. How does this duke criteria for infective endocarditis calculator work. Infective endocarditis cardiovascular disorders merck. Assesment of the duke criteria for the diagnosis of. By continuing to use our website, you are agreeing to our use of cookies. The term predisposing heart condition is used as an indication of antimicrobial prophylaxis to prevent infective endocarditis ie and as a criterion for diagnosing ie according to modified duke criteria. The clinical diagnosis of infective endocarditis ie has always been difficult and a need for a. Symptoms may include fever, small areas of bleeding into the skin, heart murmur, feeling tired, and low red blood cell count. These were originally proposed in 1994 to help establish the diagnosis of endocarditis. The duke criteria for endocarditis are summarized below. Negative predictive value of the duke criteria for infective endocarditis g. Pathologic criteria are histologic or culture confirmation of vegetation or emboli.
Modified dukes criteria for diagnosis of infective endocarditis pdf. Assesment of the duke criteria for the diagnosis of infective. Proposed modifications to the duke criteria for the diagnosis. Duke criteria for infective endocarditis radiology. Antibiotic treatment of infec tious endocarditis depends on whether the involved valve is native or. One of the reasons is that the cardiac changes do not become evident rapidly, but the fever develops fast.
These images are a random sampling from a bing search on the term duke criteria for infectious endocarditis diagnosis. Pulmonic valve endocarditis is an extremely rare infection that shares epidemiologic, clinical, radiologic, microbiologic, and prognostic features with tricuspid valve endocarditis. Duke criteria for infectious endocarditis diagnosis, endocarditis diagnosis, modified duke criteria for infectious endocarditis. Rifle criteria for classification of acute renal f. An assessment of the usefulness of the duke criteria for. Value and limitations of the duke criteria for the. The endocarditis team should have meetings on a regular basis in order to discuss cases, take surgical decisions, and define the type of followup. Modified duke infective endocarditis criteria university of.
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